Join Us

We are currently hiring lab technitianspostdocs and graduate students to work on genetic and epigenetic mechanisms of human brain complexity in health and disease. Please, contact Naiara at aquizun [at] chop.edu if interested.

Technicians

We are looking for technicians to support our work in the lab in three areas:

1-Basic lab research support.

2-Support with human embryonic stem cell and neuronal differentiation models.

3-Support with mouse colony mantainance and procedures.

4-Computational analysis related with chromatin IP and DNA and RNA sequencing

Experience in any of these three areas is strongly encouraged, but not required. Interested candidates, email your CV to Naiara (aquizun [at] chop.edu)

Graduate student position

As passionate scientists, our goal is to contribute to the foundation of future generations of bright and devoted scientists conveying both, our knowledge, as well as enthusiasm for the beauty of the scientific research. Thus, we are continuously seeking to recruit motivated and creative students and to introduce them to the fields of neurosciences, genetics and cellular biology that are intermingled in our everyday research work.

Students in our lab choose to work in one of our projects, and as they get proficient organizing, planning, and executing their experiments we encourage them to be experimentally creative and test new scientifically relevant ideas . Most projects involve aspects of modeling with pluripotent stem cells, neuronal culture and engraftments in mouse brain, gene editing with CRISPR in mouse brain and cell culture, high throughput and single cell DNA/RNA sequencing, microscopy, metabolomics and proteomics. 

Students receive training to improve their technical skills in our experimental systems, but also to improve their critical scientific reading and writing as well as oral presentation skills. We discuss about our results and research articles that we find interesting in everyday basis and in lab meetings, and we encourage students to attend and present their work in at least one relevant meeting per year. Likewise, students actively participate in preparing and submitting research articles to scientific journals and preparing successful grant applications.

If you are a student in a PhD, MD/PhD and VMD/PhD program in UPENN and are interested in learning more about our lab, contact Naiara (aquizun [at] chop.edu). We have multiple exciting rotation projects!

Rotation projects are designed to complement specific aspects of our projecs (read more) and include:

-To test gene editing strategies in human pluripotent stem cell and neuronal differentiation models

-To develop tools for epigenetic chromatin modulation during human pluripotent stem cell to neuronal differentiation

-Or to test specific hypotheses we have associated with genetic and epigenetic pathways we study in selective neuronal type developmet and degeneration.

Postdoctoral position

Postdoctoral fellows in our lab will find multiple opportunities to develop as scientists while enjoying their research.

Postdocs in our lab choose to work in two of our ongoing projects (read more) and are strongly encouraged to develop, in parallel, at least one new project that they may be interested in following up in their future scientific careers. Fellows are trained as required in research areas and experimental approaches that we work on but we welcome any expertise that they bring to the lab specially related with mouse brain surgery, behavioral studies, electrophysiology, RNA and protein biology and computational biology.

In addition to the lab work, fellows in our lab are expected to improve their writing and presentation skills, by preparing grants, scientific articles, and poster and oral presentations. They are encouraged to attend and present their work in scientifically relevant meetings and expected to participate in our weekly fun labmeetings which altogether contribute to the achievement of career developmental goals.

The strategic location of our lab within Children’s Hospital of Philadelphia and University of Pennsylvania offers multiple resources for additional career development and support that significantly complement research training. And I am sure you will also enjoy Philly!

If you recently obtained a MD or PhD (or equivalent) degree and are interested in pursuing a postdoctoral study in our lab please send 1) a cover letter 2) your CV and 3) name and contact information of three references to Naiara (aquizun [at] chop.edu)