Our Research Interest

The exponential increase of genetic studies over the last few decades has uncovered numerous genetic variants associated to neurological disorders. Often, these variants are widely expressed in every tissue and yet, they exclusively disrupt development, function or viability of specific neural populations. In fact, specific neuronal vulnerability is surprisingly common in many neurological diseases. But, why are some neurons vulnerable to disease stimuli, and why are others resistant? What determines the response of each neural type to diverse physiological and pathological conditions? And how does each neural type acquire and maintain specialized functions? These are the central questions that guide our research towards a better understanding of human brain complexity in health and diseases. READ MORE